Nature Chemical Biology DeLoache, W.C., Russ, Z.N., Narcross, L., Gonzales, A.M., Martin V.J.J., Dueber, J.E. Abstract Benzylisoquinoline alkaloids (BIAs) are a diverse family of plant-specialized metabolites that include the pharmaceuticals codeine and morphine and their derivatives. Microbial synthesis of BIAs …
An enzyme-coupled biosensor enables (S)-reticuline production in yeast from glucose Read More »
ACS Synthetic Biology Lee, M.E., DeLoache, W.C., Cervantes, B., Dueber, J.E. Abstract Saccharomyces cerevisiae is an increasingly attractive host for synthetic biology because of its long history in industrial fermentations. However, until recently, most synthetic biology systems have focused on …
A Highly-characterized Yeast Toolkit for Modular, Multi-part Assembly Read More »
Metabolic Engineering Latimer, L.N., Lee, M.E., Medina-Cleghorn, D., Kohnz, R.A., Nomura, D.K., Dueber, J.E. Abstract Fermentation of xylose, a major constituent of lignocellulose, will be important for expanding sustainable biofuel production. We sought to better understand the effects of intrinsic …
