Monthly Archives: January 2018

Employing a biochemical protecting group for a sustainable indigo dyeing strategy

Nature Chemical Biology Hsu, T.M., Welner, D.H., Russ, Z.N., Cervantes, B., Prathuri, R.L., Adams, P.D., and Dueber, J.E. Abstract Indigo is an ancient dye uniquely capable of producing the signature tones in blue denim; however, the dyeing process requires chemical

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Bioproduction of a betalain color palette in Saccharomyces cerevisiae

Metabolic Engineering Grewal, P.S., Modavi, C., Russ, Z.N., Harris, N.C., and Dueber J.E. Abstract Betalains are a family of natural pigments found exclusively in the plant order Caryophyllales. All members of this chemical family are biosynthesized through the common intermediate

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Iterative optimization of xylose catabolism in Saccharomyces cerevisiae using combinatorial expression tuning

Biotechnology and Bioengineering Latimer, L. N., & Dueber, J.E. Abstract A common challenge in metabolic engineering is rapidly identifying rate-controlling enzymes in heterologous pathways for subsequent production improvement. We demonstrate a workflow to address this challenge and apply it to

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Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways

Nature Communications Deloache, W. C., Russ, Z. N., & Dueber, J. E. Abstract Compartmentalization of enzymes into organelles is a promising strategy for limiting metabolic crosstalk and improving pathway efficiency, but improved tools and design rules are needed to make

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Application of a Palladium-Catalyzed C-H Functionalization/Indolization Method to Syntheses of cis-Trikentrin A and Herbindole B.

Angewandte Chemie Leal, R.A. Bischof, C. Lee, Y.V., Sawano, S., McAtee, C.C., Latimer, L.N., Russ, Z.N, Dueber, J.E., Yu, J., Sarpong, R. We describe herein formal syntheses of the indole alkaloids cis-trikentrin A and herbindole B from a common meso-hydroquinone intermediate prepared by a

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Tammy’s sustainable indigo dyeing paper is out

Nature article describing Tammy’s paper

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Parry and Cyrus’ betalain paper is out

1-s2.0-S1096717617302586-main (1)

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Congrats to Dr. Modavi on his graduation!

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Tammy wins Siebel award

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Shakked wins Craven Scholar award

2017 Departmental Fellows

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