Each year, the staff at Science names a significant scientific discovery as Breakthrough of the Year. This year, the genome-editing technique known as CRISP won the title. Along with the winner, Science names its top runners-up; interestingly, CRISP was runner-up twice before it eventually won the title this year. John Dueber’s yeast engineering to brew opiods was named a top nine runner-up for its ground-breaking work in engineering yeast to convert sugar into the makings of opiod painkillers.
Watch the video below for the full list of 2016 runners-up.