CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window.

Halperin, S.O., Tou, C. J., Wong, E.B., Modavi, C., Schaffer, D.V.*, and Dueber, J.E. Nature.

Employing a biochemical protecting group for a sustainable indigo dyeing strategy.

Hsu, T.M., Welner, D.H., Russ, Z.N., Cervantes, B., Prathuri, R.L., Adams, P.D., and Dueber, J.E. Nature Chemical Biology.


Bioproduction of a betalain color palette in Saccharomyces cerevisiae.

Grewal, P.S., Modavi, C., Russ, Z.N., Harris, N.C., and Dueber J.E. Metabolic Engineering.


Iterative optimization of xylose catabolism in Saccharomyces cerevisiae using combinatorial expression tuning.

Latimer, L. N., & Dueber, J.E. Biotechnology and Bioengineering.


Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways.

Deloache, W. C., Russ, Z. N., & Dueber, J. E. Nature Communications.


Microbial Factories for the Production of Benzylisoquinoline Alkaloids. Trends in Biotechnology. 34(3):228-241.

Narcross, L., Fossati, E., Bourgeois, L., Dueber, J. E., & Martin, V. J. J.


Application of a Palladium-Catalyzed C-H Functionalization/Indolization Method to Syntheses of cis-Trikentrin A and Herbindole B.

Leal, R. A., Bischof, C., Lee, Y. V., Sawano, S., McAtee, C. C., Latimer, L. N., Russ, Z. N., Dueber, J. E., Yu, J., Sarpong, R.  Angewandte Chemie.


A Barcoding Strategy Enabling Higher-Throughput Library Screening by Microscopy

Chen, R., Rishi, H. S., Potapov, V., Yamada, M. R., Yeh, V. J., Chow, T., et al.
ACS Synthetic Biology

An enzyme-coupled biosensor enables (S)-reticuline production in yeast from glucose.

DeLoache, W.C., Russ, Z.N., Narcross, L., Gonzales, A.M., Martin V.J.J., Dueber, J.E. Nature Chemical Biology

A Highly-characterized Yeast Toolkit for Modular, Multi-part Assembly.

Lee, M.E., DeLoache, W.C., Cervantes, B., Dueber, J.E.
ACS Synthetic Biology

Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds.

Zalatan, J. G., Lee, M. E., Almeida, R., Gilbert, L. A., Whitehead, E. H., La Russa, M., Tsai, J.C., Weissman, J.S., Dueber, J.E., Qi, L.S., Lim, W.A.


Selection of chromosomal DNA libraries using a multiplex CRISPR system.

Ryan, O. W., Skerker, J. M., Maurer, M. J., Li, X., Tsai, J. C., Poddar, S., Lee, M.E., DeLoache, W.C., Dueber, J.E., Arkin, A.P., Cate, J.H.D.
S eLife Sciences

Employing a combinatorial expression approach to characterize xylose utilization in Saccharomyces cerevisiae.

Latimer, L.N., Lee, M.E., Medina-Cleghorn, D., Kohnz, R.A., Nomura, D.K., Dueber, J.E. Metabolic Engineering

Avoidance of Truncated Proteins from Unintended Ribosome Binding Sites within Heterologous Protein Coding Sequences.

Whitaker, W. R., Lee, H., Arkin, A. P., Dueber, J.E.
ACS Synthetic Biology

Design and Implementation of a Biomolecular Concentration Tracker.

Hsiao, V., de Los Santos, E. L. C., Whitaker, W. R., Dueber, J. E., & Murray, R. M.
Cold Spring Harbor Laboratory

Cell-free protein synthesis: Search for the happy middle.

Russ, Z.N., Dueber, J.E.
Biotechnology Journal

Identification and characterization of a galacturonic acid transporter from Neurospora crassa and its application for Saccharomyces cerevisiae fermentation processes.

Benz, J.P., Protzko, R.J., Andrich, J.M.S., Bauer, S., Dueber, J.E., Somerville, C.R. Biotechnology for Biofuels 


Expression-level optimization of a multi-enzyme pathway in the absence of a high-throughput assay.

Lee ME, Aswani A, Han AS, Tomlin CJ, Dueber JE.
Nucleic Acids Research

Compartmentalizing metabolic pathways in organelles.

Deloache, W.C., Dueber, J.E.
Nature Biotechnology


Engineering robust control of two-component system phosphotransfer using modular scaffolds.

Whitaker WR, Davis SA, Arkin AP, Dueber JE.*
Proc.Natl Acad Sci USA

Spatial Organization of Enzymes for Metabolic Engineering.

Lee, H., DeLoache, W. and Dueber, J.E.*
Metabolic Engineering

DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency.

Conrado, R.J, Wu, G.C., Boock, J.T., Xu, H., Chen, S.Y., Lebar, T., Turnsek, J., Tomsic, N., Avbelj, M., Gaber, R., Koprivnjak, T., Mori, J., Glavnik, V., Vovk, I., Bencina, M. Hodnik, V. Anderluh, G., Dueber, J.E., Jerala, R., and DeLisa, M.P.*
Nucleic Acids Research


Metabolic Flux Enhancement by Synthetic Protein Scaffolding.

Whitaker, W.R. and Dueber, J.E.*
Methods in Enzymology


Shaking up genome engineering.

Tipton, K.A., Dueber, J.E.
Nat Biotechnol

Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli.

Moon, T.S., Dueber, J.E., Shiue, E. Prather KL.*
Metabolic Engineering

BglBricks: A flexible standard for biological part assembly.

Anderson, J.C., Dueber, J.E., Leguia, M., Wu, G.C., Goler, J.A., Arkin, A.P, Keasling, J.D.
Journal of Biological Engineering


Synthetic protein scaffolds provide modular control over flux through an engineered metabolic pathway.

Dueber, J.E.*, Wu, G.C, Malmirchegini, G.R., Moon, T.S., Petzold C.J., Ullal, A.V., Prather, K.L.J., Keasling, J.D.
Nature Biotechnology


The pathogen protein EspFU hijacks actin polymerization using mimicry and multivalency.

Sallee, N.A., Rivera, G.M., Dueber J.E., Mullins, R.D, Mayer, B.J., Lim W.A.*


Engineering synthetic signaling proteins with ultrasensitive input/output control.

Dueber, J.E., Mirsky, E.A., Lim, W.A.*
Nature Biotechnology


Rewiring cell signaling: the logic and plasticity of eukaryotic protein circuitry.

Dueber, J.E., Yeh, B.J., Bhattacharyya, R.P., Lim, W.A.*
ent Opinion in Structural Biology


Reprogramming control of an allosteric signaling switch through modular recombination.

Dueber, J.E., Yeh, B.J., Chak K., Lim, W.A.*

*Corresponding author